Gastrointestinal metabolism of monomeric and polymeric polyphenols from mango (Mangifera indica L.) bagasse under simulated conditions

Mango bagasse (MB) is an agro-industrial by-product rich in bioactive polyphenols with potential application as a functional ingredient. This study aimed to delineate the metabolic fate of monomeric/polymeric MB polyphenols subjected to simulated gastrointestinal digestion. The main identified compo...

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其他作者: Herrera-Cazares, L. Abril, Abraham, Wall-Medrano, Ramirez-Jimenez, Aurea K., Luzardo-Ocampo, Ivan, Antunez-Ricardo, Mariaelena, Loarca-Piña, Guadalupe Flavia, Gaytan-Martinez, Marcela
格式: Artículo
语言:en_US
出版: 2021
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在线阅读:https://doi.org/10.1016/j.foodchem.2021.130528
https://www.sciencedirect.com/science/article/abs/pii/S030881462101534X
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总结:Mango bagasse (MB) is an agro-industrial by-product rich in bioactive polyphenols with potential application as a functional ingredient. This study aimed to delineate the metabolic fate of monomeric/polymeric MB polyphenols subjected to simulated gastrointestinal digestion. The main identified compounds by LC/MS-TOF-ESI were phenolic acids [gallic acid (GA) and derivates, and chlorogenic acid], gallotannins and derivatives [di-GA (DA) and 3GG-to-8GG], benzophenones [galloylated maclurins (MGH, MDH)], flavonoids [Quercetin (Quer) and (QuerH)] and xanthones [mangiferin isomers]. The bioaccessibility depended on the polyphenols’ structure, being Quer, 5G to 8G the main drivers. The results suggested that the gastrointestinal fate of MB polyphenols is mainly governed by benzophenones and gallotannins degalloylation and spontaneous xanthone isomerization in vitro to sustain GA bioaccessibility.