Preparation of Silver-Doped Alumina Spherical Beads with Antimicrobial Properties

The synthesis of composites with antibacterial properties is of great interest for the development of new biomedical applications. The antimicrobial properties of silver have been verified against microorganisms such as bacteria, viruses, and fungi; interest in silver has been renewed, so several te...

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第一著者: Roque Ruiza, Jose Hafid
その他の著者: Castillo Ramirez, Daniela, Ruiz Baltazar, Jose de Jesus, Espinosa Cristóbal, León Francisco, Reyes-López, Simón Yobanny
フォーマット: Artículo
言語:en_US
出版事項: 2018
主題:
オンライン・アクセス:https://doi.org/10.1155/2018/7127843
https://www.hindawi.com/journals/jnm/2018/7127843/
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その他の書誌記述
要約:The synthesis of composites with antibacterial properties is of great interest for the development of new biomedical applications. The antimicrobial properties of silver have been verified against microorganisms such as bacteria, viruses, and fungi; interest in silver has been renewed, so several technologies are currently in development, especially in dental materials. The purpose of this work was to improve the parameters for producing silver-doped alumina spherical beads using sodium alginate as a sacrificial template. Alumina is a biocompatible and thermally stable ceramic, while silver was used for its bactericidal properties. The obtained spheres presented a mean diameter of 2 mm, with an irregular surface and intertwined particles after a sintering process. After electrodeposition, white spheres turned to a dark gray color, demonstrating the presence of silver nanoparticles and fractal silver dendrites on the surface. Spheres were characterized by SEM, FTIR, and XRD. Antimicrobial activity of the alumina-AgP spheres against E. coli, S. aureus, K. pneumoniae, and S. mutans was analyzed by turbidimetry. The specific antimicrobial activity of all the composites showed specific antibacterial effects, independently of the amount of silver deposited, probably due to the differences in the microbial cell wall structures. Therefore, antibacterial activity depends on microbiological and structural characteristics of each bacterium.