The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent

The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent

During inflammatory responses, monocytes are recruited into inflamed tissues, where they become monocyte-derived macrophages and acquire pro-inflammatory and tissue-damaging effects in response to the surrounding environment. In fact, monocyte-derived macrophage subsets are major pathogenic cells in...

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Altri autori: Cuevas, Víctor D., Orta Zavalza, Emmanuel, Simón-Fuentes, Miriam, Samaniego, Rafael, Sánchez-Mateos, Paloma, Escribese, María, Cimas, Francisco J., Bustos, Matilde, Pérez-Diego, Mario, Ocaña, Alberto, Domínguez-Soto, Ángeles, Vega, Miguel Á., Corbí, Ángel L.
Natura: Artículo
Lingua:English
Pubblicazione: 2021
Soggetti:
Inflammation
Interleukin-10
Macrophage
Macrophage polarization
info:eu-repo/classification/cti/3
Accesso online:https://doi.org/10.1159/000519305
https://www.karger.com/Article/FullText/519305
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