The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains

Histidine kinases are key bacterial sensors that recognize diverse environmental stimuli. While mechanisms of phosphorylation and phosphotransfer by cytoplasmic kinase domains are relatively well-characterized, the ways in which extracytoplasmic sensor domains regulate activation remain mysterious....

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Bibliographic Details
Other Authors: Cho, Timothy, Malpica, Roxana, Murray, Cameron, Margain-Quevedo, Rodrigo, Thede, Gina L, Lu, Jun, Edwards, Ross A., Glover, J. N. Mark, Raivio, Tracy L.
Format: Artículo
Language:English
Published: 2024
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Online Access:https://doi.org/10.1016/j.jbc.2024.107265
https://doi.org/10.1016/j.jbc.2024.107265
https://www.jbc.org/article/S0021-9258(24)01766-6/fulltext
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